diff --git a/conn.go b/conn.go
index f256b714..97500229 100644
--- a/conn.go
+++ b/conn.go
@@ -50,6 +50,7 @@ type Conn struct {
 	causeOfDeath       error
 	logger             Logger
 	mr                 msgReader
+	fp                 *fastpath
 }
 
 type PreparedStatement struct {
diff --git a/fastpath.go b/fastpath.go
new file mode 100644
index 00000000..5eee1ea1
--- /dev/null
+++ b/fastpath.go
@@ -0,0 +1,110 @@
+package pgx
+
+import (
+	"encoding/binary"
+)
+
+type fastpathArg []byte
+
+func newFastpath(cn *Conn) *fastpath {
+	return &fastpath{cn: cn, fns: make(map[string]Oid)}
+}
+
+type fastpath struct {
+	cn  *Conn
+	fns map[string]Oid
+}
+
+func (f *fastpath) functionOID(name string) Oid {
+	return f.fns[name]
+}
+
+func (f *fastpath) addFunction(name string, oid Oid) {
+	f.fns[name] = oid
+}
+
+func (f *fastpath) addFunctions(rows *Rows) error {
+	for rows.Next() {
+		var name string
+		var oid Oid
+		if err := rows.Scan(&name, &oid); err != nil {
+			return err
+		}
+		f.addFunction(name, oid)
+	}
+	return rows.Err()
+}
+
+type fpArg []byte
+
+func fpIntArg(n int32) fpArg {
+	res := make([]byte, 4)
+	binary.BigEndian.PutUint32(res, uint32(n))
+	return res
+}
+
+func fpInt64Arg(n int64) fpArg {
+	res := make([]byte, 8)
+	binary.BigEndian.PutUint64(res, uint64(n))
+	return res
+}
+
+func (f *fastpath) Call(oid Oid, args []fpArg) (res []byte, err error) {
+	wbuf := newWriteBuf(f.cn.wbuf[:0], 'F') // function call
+	wbuf.WriteInt32(int32(oid))             // function object id
+	wbuf.WriteInt16(1)                      // # of argument format codes
+	wbuf.WriteInt16(1)                      // format code: binary
+	wbuf.WriteInt16(int16(len(args)))       // # of arguments
+	for _, arg := range args {
+		wbuf.WriteInt32(int32(len(arg))) // length of argument
+		wbuf.WriteBytes(arg)             // argument value
+	}
+	wbuf.WriteInt16(1) // response format code (binary)
+	wbuf.closeMsg()
+
+	if _, err := f.cn.conn.Write(wbuf.buf); err != nil {
+		return nil, err
+	}
+
+	for {
+		var t byte
+		var r *msgReader
+		t, r, err = f.cn.rxMsg()
+		if err != nil {
+			return nil, err
+		}
+		switch t {
+		case 'V': // FunctionCallResponse
+			data := r.readBytes(r.readInt32())
+			res = make([]byte, len(data))
+			copy(res, data)
+		case 'Z': // Ready for query
+			f.cn.rxReadyForQuery(r)
+			// done
+			return
+		default:
+			if err := f.cn.processContextFreeMsg(t, r); err != nil {
+				return nil, err
+			}
+		}
+	}
+}
+
+func (f *fastpath) CallFn(fn string, args []fpArg) ([]byte, error) {
+	return f.Call(f.functionOID(fn), args)
+}
+
+func fpInt32(data []byte, err error) (int32, error) {
+	if err != nil {
+		return 0, err
+	}
+	n := int32(binary.BigEndian.Uint32(data))
+	return n, nil
+}
+
+func fpInt64(data []byte, err error) (int64, error) {
+	if err != nil {
+		return 0, err
+	}
+	return int64(binary.BigEndian.Uint64(data)), nil
+}
diff --git a/large_objects.go b/large_objects.go
new file mode 100644
index 00000000..b208aede
--- /dev/null
+++ b/large_objects.go
@@ -0,0 +1,146 @@
+package pgx
+
+import (
+	"io"
+)
+
+// LargeObjects is a structure used to access the large objects API. It is only
+// valid within the transaction where it was created.
+//
+// For more details see: http://www.postgresql.org/docs/current/static/largeobjects.html
+type LargeObjects struct {
+	// Has64 is true if the server is capable of working with 64-bit numbers
+	Has64 bool
+	fp    *fastpath
+}
+
+const largeObjectFns = `select proname, oid from pg_catalog.pg_proc 
+where proname in (
+'lo_open', 
+'lo_close', 
+'lo_create', 
+'lo_unlink', 
+'lo_lseek', 
+'lo_lseek64', 
+'lo_tell', 
+'lo_tell64', 
+'lo_truncate', 
+'lo_truncate64', 
+'loread', 
+'lowrite') 
+and pronamespace = (select oid from pg_catalog.pg_namespace where nspname = 'pg_catalog')`
+
+// LargeObjects returns a LargeObjects instance for the transaction.
+func (tx *Tx) LargeObjects() (*LargeObjects, error) {
+	if tx.conn.fp == nil {
+		tx.conn.fp = newFastpath(tx.conn)
+	}
+	if _, exists := tx.conn.fp.fns["lo_open"]; !exists {
+		res, err := tx.Query(largeObjectFns)
+		if err != nil {
+			return nil, err
+		}
+		if err := tx.conn.fp.addFunctions(res); err != nil {
+			return nil, err
+		}
+	}
+
+	lo := &LargeObjects{fp: tx.conn.fp}
+	_, lo.Has64 = lo.fp.fns["lo_lseek64"]
+
+	return lo, nil
+}
+
+type LargeObjectMode int32
+
+const (
+	LargeObjectModeWrite LargeObjectMode = 0x20000
+	LargeObjectModeRead  LargeObjectMode = 0x40000
+)
+
+// Create creates a new large object. If id is zero, the server assigns an
+// unused OID.
+func (o *LargeObjects) Create(id Oid) (Oid, error) {
+	newOid, err := fpInt32(o.fp.CallFn("lo_create", []fpArg{fpIntArg(int32(id))}))
+	return Oid(newOid), err
+}
+
+// Open opens an existing large object with the given mode.
+func (o *LargeObjects) Open(oid Oid, mode LargeObjectMode) (*LargeObject, error) {
+	fd, err := fpInt32(o.fp.CallFn("lo_open", []fpArg{fpIntArg(int32(oid)), fpIntArg(int32(mode))}))
+	return &LargeObject{fd: fd, lo: o}, err
+}
+
+// Unlink removes a large object from the database.
+func (o *LargeObjects) Unlink(oid Oid) error {
+	_, err := o.fp.CallFn("lo_unlink", []fpArg{fpIntArg(int32(oid))})
+	return err
+}
+
+// A LargeObject is a large object stored on the server. It is only valid within
+// the transaction that it was initialized in. It implements the these interfaces:
+//
+// - io.Writer
+// - io.Reader
+// - io.Seeker
+// - io.Closer
+type LargeObject struct {
+	fd int32
+	lo *LargeObjects
+}
+
+// Write writes
+func (o *LargeObject) Write(p []byte) (int, error) {
+	n, err := fpInt32(o.lo.fp.CallFn("lowrite", []fpArg{fpIntArg(o.fd), p}))
+	return int(n), err
+}
+
+// Read reads up to len(p) bytes into p returning the number of bytes read.
+func (o *LargeObject) Read(p []byte) (int, error) {
+	res, err := o.lo.fp.CallFn("loread", []fpArg{fpIntArg(o.fd), fpIntArg(int32(len(p)))})
+	if len(res) < len(p) {
+		err = io.EOF
+	}
+	return copy(p, res), err
+}
+
+// Seek moves the current location pointer to the new location specified by offset.
+func (o *LargeObject) Seek(offset int64, whence int) (n int64, err error) {
+	if o.lo.Has64 {
+		n, err = fpInt64(o.lo.fp.CallFn("lo_lseek64", []fpArg{fpIntArg(o.fd), fpInt64Arg(offset), fpIntArg(int32(whence))}))
+	} else {
+		var n32 int32
+		n32, err = fpInt32(o.lo.fp.CallFn("lo_lseek", []fpArg{fpIntArg(o.fd), fpIntArg(int32(offset)), fpIntArg(int32(whence))}))
+		n = int64(n32)
+	}
+	return
+}
+
+// Tell returns the current read or write location of the large object
+// descriptor.
+func (o *LargeObject) Tell() (n int64, err error) {
+	if o.lo.Has64 {
+		n, err = fpInt64(o.lo.fp.CallFn("lo_tell64", []fpArg{fpIntArg(o.fd)}))
+	} else {
+		var n32 int32
+		n32, err = fpInt32(o.lo.fp.CallFn("lo_tell", []fpArg{fpIntArg(o.fd)}))
+		n = int64(n32)
+	}
+	return
+}
+
+// Trunctes the large object to size.
+func (o *LargeObject) Truncate(size int64) (err error) {
+	if o.lo.Has64 {
+		_, err = o.lo.fp.CallFn("lo_truncate64", []fpArg{fpIntArg(o.fd), fpInt64Arg(size)})
+	} else {
+		_, err = o.lo.fp.CallFn("lo_truncate", []fpArg{fpIntArg(o.fd), fpIntArg(int32(size))})
+	}
+	return
+}
+
+// Close closees the large object descriptor.
+func (o *LargeObject) Close() error {
+	_, err := o.lo.fp.CallFn("lo_close", []fpArg{fpIntArg(o.fd)})
+	return err
+}
diff --git a/large_objects_test.go b/large_objects_test.go
new file mode 100644
index 00000000..a19c851d
--- /dev/null
+++ b/large_objects_test.go
@@ -0,0 +1,121 @@
+package pgx_test
+
+import (
+	"io"
+	"testing"
+
+	"github.com/jackc/pgx"
+)
+
+func TestLargeObjects(t *testing.T) {
+	t.Parallel()
+
+	conn, err := pgx.Connect(*defaultConnConfig)
+	if err != nil {
+		t.Fatal(err)
+	}
+
+	tx, err := conn.Begin()
+	if err != nil {
+		t.Fatal(err)
+	}
+
+	lo, err := tx.LargeObjects()
+	if err != nil {
+		t.Fatal(err)
+	}
+
+	id, err := lo.Create(0)
+	if err != nil {
+		t.Fatal(err)
+	}
+
+	obj, err := lo.Open(id, pgx.LargeObjectModeRead|pgx.LargeObjectModeWrite)
+	if err != nil {
+		t.Fatal(err)
+	}
+
+	n, err := obj.Write([]byte("testing"))
+	if err != nil {
+		t.Fatal(err)
+	}
+	if n != 7 {
+		t.Errorf("Expected n to be 7, got %d", n)
+	}
+
+	pos, err := obj.Seek(1, 0)
+	if err != nil {
+		t.Fatal(err)
+	}
+	if pos != 1 {
+		t.Errorf("Expected pos to be 1, got %d", pos)
+	}
+
+	res := make([]byte, 6)
+	n, err = obj.Read(res)
+	if err != nil {
+		t.Fatal(err)
+	}
+	if string(res) != "esting" {
+		t.Errorf(`Expected res to be "esting", got %q`, res)
+	}
+	if n != 6 {
+		t.Errorf("Expected n to be 6, got %d", n)
+	}
+
+	n, err = obj.Read(res)
+	if err != io.EOF {
+		t.Error("Expected io.EOF, go nil")
+	}
+	if n != 0 {
+		t.Errorf("Expected n to be 0, got %d", n)
+	}
+
+	pos, err = obj.Tell()
+	if err != nil {
+		t.Fatal(err)
+	}
+	if pos != 7 {
+		t.Errorf("Expected pos to be 7, got %d", pos)
+	}
+
+	err = obj.Truncate(1)
+	if err != nil {
+		t.Fatal(err)
+	}
+
+	pos, err = obj.Seek(-1, 2)
+	if err != nil {
+		t.Fatal(err)
+	}
+	if pos != 0 {
+		t.Errorf("Expected pos to be 0, got %d", pos)
+	}
+
+	res = make([]byte, 2)
+	n, err = obj.Read(res)
+	if err != io.EOF {
+		t.Errorf("Expected err to be io.EOF, got %v", err)
+	}
+	if n != 1 {
+		t.Errorf("Expected n to be 1, got %d", n)
+	}
+	if res[0] != 't' {
+		t.Errorf("Expected res[0] to be 't', got %v", res[0])
+	}
+
+	err = obj.Close()
+	if err != nil {
+		t.Fatal(err)
+	}
+
+	err = lo.Unlink(id)
+	if err != nil {
+		t.Fatal(err)
+	}
+
+	_, err = lo.Open(id, pgx.LargeObjectModeRead)
+	if e, ok := err.(pgx.PgError); !ok || e.Code != "42704" {
+		t.Errorf("Expected undefined_object error (42704), got %#v", err)
+	}
+}